Microtubule Protein Streaming Toward the Edges of the Cell

Cytoplasmic linker protein (CLIP)-170 regulates microtubule dynamics and links microtubule ends to different intracellular structures. In this video, the gene for CLIP-170 has been fused with green florescent protein (GFP). When the protein is expressed in cells, the activities can be monitored in real time. Here, CLIP-170 streams toward the edges of the cell. See the NIGMS web page on Live Cell Imaging [https://www.nigms.nih.gov/Research/specificareas/cellimaging/Pages/livecellimaging.aspx] for related information. Credit: Gary Borisy, Marine Biological Laboratory.